.NET Reflector generates a store of decompiled code and debug symbols on your hard drive (a set of directories in your local settings), enabling you to step-through debug the selected assemblies. The store retains the decompiled code and symbols, so that you do not need to decompile every time.

To delete the contents of the store:

1. Open the Debug and Decompile dialog box.
   See Decompiling assemblies for details on how to do this.
2. Click Clear Store.
   Depending on the size of the store, it may take a few minutes to be clear the store.

You will need to reselect and decompile any assemblies that were previously debugged.